« FDA's Lousy Christmas Present | Main | Darwin's Big Toe »

January 26, 2009



I also prescribe lyrica for neuropathic conditions and fibromyalgia. In fact, I've prescribed it to psychiatric patients. I came across this warning recently myself through the CMA website's drug database. It is an FDA warning and not canadian as you pointed out. The risk is <1% but certainly greater compared to placebo. Higher in the epileptic group. Like yourself I am uncertain of how to proceed - to warn or not to warn? Usually canada is the slowest to take on "new" drugs through rigourous R&D. Stringent standards would expect such warnings to be listed here if a concern. Hmm....


I warn them now because as a specialist I can't monitor them closely enough after prescribing the stuff. I also inform their primary physician through my consultation letter and figure that if everyone is aware, chances are less we will have a problem. The down side, of course, is that the patients' worries about the drug might worsen their baseline anxiety.
By the way, did you get the FDA advisory only after looking up the drug or was there some kind of notice to the general medical viewer of the CMA site? Where on the CMA site did you find it? I didn't see it on the Health Canada advisory web site.


It is in the drug database on the cma website. Search for pregablin/lyrica and you'll see the warning FDA issued.
Health canada is "looking into it" and has not issued an advisory as of yet. Lyrica is a wonderful drug and I to am afraid of turning people off it by adding that caveat. Certainly an ethical dilemma.

e cigarettes

I am beginning to really lose all faith and credibility in the FDA. It seems to me that instead of focusing their efforts on protecting the general public they are in-turn being influenced by corporate agenda and special interest. I take everything they say with a grain of salt.


France captain Patrice Evra claims that coach Raymond Domenech dropped him from the squad for "no valid reason'' and denied him the chance to apologise to the French public by reading out the players' statement himself.

Maria Decosta

I've used Lyrica for a while now and it seems that my body is getting so used to the drug that it's not working like it first did. I take 75mg in the morning and 75mg at bedtime. I either need to increase my dose or find something else that will work. It's hard to function during my days because of the pain.


Terri Wills

On Jan 22, 2009 I was admitted to hospital in a coma resulting from a intentional overdose. I'm convinced it was because of Lyrica. I remained in hospital on life support for three months and remained an additional six months after that where I required eight major surgeries.

My inability to cope with the unrelenting suicidal ideation outweighed the skills I had to cope with it.

My family physician had increased my Lyrica perscription from 150mg per day to triple that amount. Six weeks later I gave in to the ideation.

I've been out of hospital now 18 months and took Lyrica once since that time. I immediately had vision problems then some pretty strange thoughts. My daughter asked what medication I had taken and she identified the Lyrica. It was only then that I recognized the probability could not be ruled-out because I had not experienced that depressed mood since my hospitalization. I will never take Lyrica again. Do I believe it's a good drug for neuralgia? Yes, I do! Do I believe it is for everyone? No, I know it isn't. I absolutely believe I would commit suicide if I were to resume taking Lyrica again. I could never be convinced that the best psychological skills employed could EVER overcome the exhausting and unrelenting thoughts that death was the only viable means of coping with those thoughts.

The comments to this entry are closed.